Tirosint® generic is Levothyroxine Sodium Capsules
Levothyroxine Sodium Capsules USP, an authorized generic of Tirosint®.
Levothyroxine sodium is indicated for the treatment of hypothyroidism – as replacement therapy in primary, secondary, and tertiary congenital or acquired hypothyroidism.
Levothyroxine Sodium Capsules, a unique gel-cap formulation designed to address concerns of absorption and tolerability commonly found in levothyroxine tablets. The capsules contain only four simple ingredients: levothyroxine, gelatin, glycerin and water, and are free from sugars, dyes, alcohol, wheat starch (gluten), and lactose[i]. This is especially important for patients with hypothyroidism who have allergies or sensitivities to ingredients commonly found in levothyroxine tablets or for those with certain gastrointestinal conditions.[ii] |
When patients were switched from levothyroxine tablets to gel caps, the majority experienced significant reductions in dose changes and significant improvement in hypothyroid symptom control.[iii] |
The results of the study were consistent regardless of the reason for medication switch (efficacy or adverse effects) or prior therapy (branded or generic levothyroxine tablets).3 |
The generic product is available as 13mcg, 25mcg, 50mcg, 75mcg, 88mcg, 100mcg, 112mcg, 125mcg, 137mcg, 150mcg, 175mcg, and 200mcg strength capsules.
[1] Levothyroxine Sodium Capsules. Parsippany, NJ: YARAL Pharma Inc; 2021.
[1] McMillan M, Rotenberg KS, Vora K, et al. Comorbidities, concomitant medications, and diet as factors affecting levothyroxine therapy; results of the CONTROL Surveillance Project. Drugs in R&D. 2015;16(1):53-68.
[1] Ernst FR, Sandulli W, Elmor R, Welstead J, Sterman AB, Lavan M. Retrospective Study of Patients Switched from Tablet Formulations to a Gel Cap Formulation of Levothyroxine: Results of the CONTROL Switch Study. Drugs R D. 2017 Mar;17(1):103-115. doi: 10.1007/s40268-016-0150-z. PMID: 27943146; PMCID: PMC5318319.